Police and ambulance staff descended upon Woodbury Close on Monday afternoon.
A spokesman for West Midlands Ambulance Service said crews were called at about 2.44pm to a medical emergency at a property.
A statement read: “We were called to a medical emergency at a private residential property in Brierley Hill at 2.44pm on Monday.
“A paramedic officer, critical care paramedic and two ambulances attended the scene. Sadly a woman was confirmed deceased on scene.”
A spokesman for West Midlands Police confirmed the woman’s death is not being treated as suspicious.
He said: “We were called to an address in Woodbury Close, Brierley Hill, at 3.45pm yesterday.
“On arrival, we found that a woman had sadly died. Her death is not being treated as suspicious.”
